For sure run calibration and that should get things pretty close, if not exact. If placement is critical though, I’d still test before running your file just to make sure. One easy way is to add a round vector to your file. Get your file and the round line all lined up and then upload it all together. (Make sure the round line is a different color so you can adjust the setting independently of the other file parts.) Mask your board and then turn off everything in the file but the round line and run that with a power of 3 or so. (Just enough power to mark the masking, but not burn through it to your material.) That will show you exactly where the file will engrave. Once you have everything where you want it, turn off the round test vector and run your engraving.
There are several similar ways to go about this and this is just one example. Another version is to upload the file and round vector test line, secure tape or a piece of paper to the tray and run the round line. That will give you a target to lay your material on.