I have a moderate red/green deficiency. I don’t have any problems with Inkscape. I just use high contrast colors and layers to keep everything straight. Also, I can always use the eye dropper tool as a crutch if need be. I may not be able to see the difference between some colors, but I can read RGBA hex codes just fine.
The colors used in the GFUI are luckily outside of my confusion zones, but I do find the lack of value separation bothersome. It reminds me of when Solidworks switched over from color icons to icons that were all just shades of blue and gray.