I’ve tried Sculptris, Netfabb and Meshmixer. Had very iffy results, although to be honest I was shooting for specific mesh modifications that had to be clean of non-manifold edges and self-intersections. It really made a mess and I wound up taking it into Rhino and doing it manually. Maybe in this case they would work better, but I’d be afraid they would introduce some weird results if not used correctly. (For that matter, F360 and Rhino might as well.) I hate messing with meshes.
F360 has a sculpting option that I’ve been wanting to play with. It’s a separate section from the regular sketches and geometry. It might actually work all right for this. It looks easy enough to use from the vids, but I haven’t had a chance to get into anything specific yet.
You might be right that Blender is the best choice though. (Never tried it.) It’s another option.