I think it will come down to the individual and your ventilation setup more than anything.
In general, it’s best to wear a mask and work in well-ventilated spaces when sanding any kind of wood. if you follow those protocols and don’t have a direct allergic reaction, you’ll probably be ok.
If your laser vent setup is well sealed, (and/or you add a booster fan or GF ever decides to let us turn the fan on as we please [come on guys we want it]) you shouldn’t have much exposure to the smoke at all. If you’re really worried, you could also get a full on charcoal mask for when you are loading/unloading the GF.
I cut and work with lots of weirder woods, and have yet to have any serious reaction to anything following these protocols. The worst reaction I have is to baltic plywood smoke [it makes my throat feel weird sometimes], I suspect from the glues. I take care to stay away from the smoke as much as possible then.