It is possibly to score the cardboard but I generally don’t.
Unlike normal scoring where you crush the fibres to make it easy to fold the laser cutter actually cuts halfway through the paper, when you come to fold it I found the the cardboard de laminates (comes apart in the middle) and the whole fold can go a bit floppy.
I now do my folds with dotted lines, then the cardboard is either cut or not cut and the whole things is faster and more reliable anyway.