Go with another vent out a window if you can. Your laundry is going to smell like a campfire. (Or worse…acrylic and leather are gag-inducing.)
You do want to stay with the machine while a job is running, and that can run up to a couple hours for large engraves, so if you can find a spot near a window in your office, it’s a much more comfortable arrangement. (I got rid of a couple of printers to make room for it.)
For design software, Inkscape is good, a lot of people use it. Illustrator is excellent if you want a paid option. Fusion 360 is good for the fancy 3D stuff, but do yourself a favor and get comfortable with the 2D design software like Inkscape or Illustrator before diving into Fusion. You have to use either of those to convert the Fusion files anyway. And designing using vector drawing programs is different enough from raster design (Photoshop) that you have got a little bit of a learning curve ahead of you.
Don’t try to switch between drawing programs. They all do the same things, but it will be confusing if you start to learn one and then try to jump to another one. (Everyone hides the operations in different places, under different menus. It just takes getting used to where things are, and that comes over time as you get comfortable with it.)
You will definitely want to read through the Starter Tutorials that Glowforge puts out to get comfortable with the process here:
And there are a series of design tutorials here that will put you way ahead of the curve if you take the time to read them before getting started:
Anyway…you’re gonna love it! Welcome to the forum. 