I have an inhouse vac system in my home that is not used. The unit is in the garage where i will be setting up my GF.
The system as a 2" exsaust pipe that leads outside. Initially I thought of using the exhaust pipe and a 4-inch inline fan to vent. My buddy said why not use the entire vac system precluding the need for an inline fan.
I am going to jump on the “bad idea” side here. I think you would greatly regret it if you tried to use your 2" pipe system. It could make your whole house smell and damage vacuum and possibly the if the output is lacking. And it would be nearly impossible to clean.
I m sure you know this already, but there is an operating temperature range for the So depending on where you live you will have to regulate the space to operate.
Aside from everyone’s input on the 2" size, the other reason i would think. is the vacuum units I have experience with are LOUD! The inline fan is in a lot of installations intended to make things quieter.
If your(or the next owner) ever wanting to use it again, putting the exhaust from the would almost certainly make that not possible.
I was thinking that since the system was dragging from inside the house, that it could go to an inclosed area around the Glowforge making it a lot cooler, then an external fan through a hole made 4:" or 6" as the external was sized.