Open up your design in a raster art program, and click Adjustments > Invert Colours (That’s PaintNet, all programs will have something like that)
This is the original on the left, and the inverted on the right
If you put this in the machine it will engrave the black area, but leave the white untouched - which should make it clearer on a clear acrylic. An example of an image on clear acrylic: Gandalf Acrylic Key Ring (that one may also be helped by covering 90% of the surface!)