That was my first question to GF before I bought it, and the answer was, “I don’t know” and as I’ve read more on the forum, I think my answer is, “hm, I don’t think I should try it”. Polymer Clay is - well, it depends on the formula of the brand - but essentially, it bakes into hard plastic. So, I have a feeling that laser fumes would be dangerous. (When I sand the stuff, I use wet sandpaper and wear a mask - you do not want to breathe in particles of plastic.)
That said, I’m still really excited to get the GF to create nifty little boxes to cover in polymer clay, and to make lamp-skeletal structures into which I can slide flat glass panels. (Drilling holes in apothecary jars to make lamps is not fun. Though, the apothecary-lamp-shapes are nifty.) Lots more lamp-related projects w/GF - I’ll be forging lamp-bases of wood to support polymer-clay covered glass globes, etc. Can’t wait!