It’ll depend on the design, I chose that one because it didn’t have any islands (wanted a quick 2 piece insert inlay) and then sized it how I wanted it. After that I tweaked stroke size until the smallest gaps between flake bits were at least about 1mm,
If you’re engraving, you can go way smaller. If you’re cutting, acrylic can melt and slump if you cut it very thin.
You might be able to mitigate that by Cutting it in stages to let the acrylic cool before you cut skinny pieces (cut one edge. Stop and cool. Cut other edge,) but that’s mostly theoretical, I’ve never tried it.