Here is something I made a longtime ago on my CNC using a depth map and CAM software(I think it was mastercam ART) dark areas are the thickest. I think the 3D engrave would do this with ease!
Got the idea from old porcelain lamp shades.
Here it is not back lit, kind of creepy
It was machined from 1/4 white acrylic, step over was maybe .005.